정신건강의학과
김용식 교수
- [전문분야]
- 조현병, 양극성 장애, 초기 정신병 / 만 17세 이상
- [전문진료]
- 주요 정신병

논문
- Behavioral and transcriptional effects of repeated electroconvulsive seizures in the neonatal MK-801-treated rat model of schizophrenia, Psychopharmacology (Berl). 2024
Change in absolute neutrophil count after COVID-19 infection in patients using clozapine versus other antipsychotics, Int Clin Psychopharmacol . 2024
Association between initial clozapine titration and pneumonia risk among patients with schizophrenia in a Korean tertiary hospital, Schizophr Res. 2023
Association between initial pattern of clozapine titration, concentration-to-dose ratio, and incidence of fever in patients with schizophrenia spectrum disorders in a Korean tertiary hospital, Schizophr Res, 2023
Electroconvulsive Seizure Normalizes Motor Deficits and Induces Autophagy Signaling in the MPTP-Induced Parkinson Disease Mouse Model, Psychiatry Investig. 2023
Electroconvulsive Seizure Normalizes Motor Deficits and Induces Autophagy Signaling in the MPTP-Induced Parkinson Disease Mouse Model, Psychiatry Investig 2023
Clozapine Blood Concentration Predicts Corrected QT-Interval Prolongation in Patients with Psychoses. J Clin Psychopharmacology. 2022 Nov
Electroconvulsive seizure inhibits the mTOR signaling pathway via AMPK in the rat frontal cortex. Psychopharmacology. 2022
Clozapine Titration Safer by Using Six Ancestry-Based Personalized Dosing Titrations, CRP, and Clozapine Levels, Pharmacopsytchiatry, 2022
An International Adult Guideline for Making Clozapine Titration Safer by Using Six Ancestry-Based Personalized Dosing Titrations, CRP, and Clozapine Levels, Pharmacopsytchiatry, 2022
Challenges in prescribing clozapine in the era of COVID-19: a review focused on immunological implications Clin Psychopharmacol Neurosci . 2021
Effect of liraglutide 3.0mg treatment on weight reduction in obese antipsychotic-treated patients Psychiatry Res, 2021
Resolution of persistent auditory verbal hallucinations after long-term ECT maintenance: A case report of a patient with clozapine-resistant schizophrenia, Clin Psychopharmacol Neurosci 2021
Electroconvulsive Seizures Induce Autophagy by Activating the AMPK Signaling Pathway in the Rat Frontal Cortex. Int J Neuropsychopharmacol. 2020
Initial Seizure Threshold in Brief-Pulse Bilateral Electroconvulsive Therapy in Patients with Schizophrenia or Schizoaffective Disorder. Psychiatry Investig. 2019
Long-Term Changes in Self-Report Auditory Verbal Hallucinations in Patients with Schizophrenia Using Clozapine. Psychiatry Investig. 2019
Association between electroencephalogram changes and plasma clozapine levels in clozapine-treated patients. Int Clin Psychopharmacol. 2019
Combination of Electroconvulsive Therapy and Clozapine in Treatment-Resistant Schizophrenia. Psychiatry Investig. 2018
Electroconvulsive Seizure Alters the Expression and Daily Oscillation of Circadian Genes in the Rat Frontal Cortex. Psychiatry Investig. 2018
Long-Term Evolution of Metabolic Status in Patients with Schizophrenia Stably Maintained on Second-Generation Antipsychotics. Psychiatry Investig. 2018
The antipsychotic agent clozapine induces autophagy via the AMPK-ULK1-Beclin1 signaling pathway in the rat frontal cortex. Prog Neuropsychopharmacol Biol Psychiatry. 2018
Comparison of clinician-rated and self-report insight in Korean patients with schizophrenia using VAGUS insight scale. Psychiatry Res. 2017
Effectiveness of Electroconvulsive Therapy Augmentation on Clozapine-Resistant Schizophrenia. Psychiatry Investig. 2017
Clozapine Improves Memory Impairment and Reduces Aβ Level in the Tg-APPswe/PS1dE9 Mouse Model of Alzheimer's Disease. Mol Neurobiol. 2017
Sex-specific association between the albumin D-element binding protein gene and metabolic syndrome in patients with bipolar disorder and schizophrenia. Psychiatry Res. 2016
The longitudinal trends in the relationship between drug-induced extrapyramidal symptoms and personal and social performance in a population of the patients with schizophrenia: A latent growth model. Psychiatry Res. 2016
Longitudinal relationship between Personal and Social Performance (PSP) and anxiety symptoms in schizophrenia. J Affect Disord. 2016
Neurocognitive functioning as an intermediary variable between psychopathology and insight in schizophrenia. Psychiatry Res. 2015
Differences in the internal structure of hallucinatory experiences between clinical and nonclinical populations. Psychiatry Res. 2015
Evaluating subjective domains of antipsychotic-induced adverse effects using heart rate variability. Psychiatry Clin Neurosci. 2015
Refinement of the SWN-20 based on the Rasch rating model. Compr Psychiatry. 2015
Clozapine induces chloride channel-4 expression through PKA activation and modulates CDK5 expression in SH-SY5Y and U87 cells. Prog Neuropsychopharmacol Biol Psychiatry. 2015
Leptin is associated with mood status and metabolic homeostasis in patients with bipolar disorder. Neuropsychobiology. 2014
Genetic Role of BDNF Val66Met and 5-HTTLPR Polymorphisms on Depressive Disorder. Psychiatry Investig. 2014
Aminotransferase levels as a prospective predictor for the development of metabolic syndrome in patients with schizophrenia. Psychopharmacology (Berl). 2014
Repeated treatment with electroconvulsive seizures induces HDAC2 expression and down-regulation of NMDA receptor-related genes through histone deacetylation in the rat frontal cortex. Int J Neuropsychopharmacol. 2014
A prospective, open-label study to evaluate symptomatic remission in schizophrenia with risperidone long-acting injectable in Korea. Int Clin Psychopharmacol. 2014
Influencing Factors and Predictors of Early Response in Schizophrenia Patients Receiving the Paliperidone Extended-Release Tablets (Paliperidone ER). Psychiatry Investig. 2013
Electroconvulsive shock increases SIRT1 immunoreactivity in the mouse hippocampus and hypothalamus. J ECT. 2013
Egr1 regulates lithium-induced transcription of the Period 2 (PER2) gene. Biochim Biophys Acta. 2013
Role of MKP-1 (DUSP1) in clozapine-induced effects on the ERK1/2 signaling pathway in the rat frontal cortex. Psychopharmacology (Berl). 2013
Intercultural differences in factor structure of the SWN-20 in patients with schizophrenia. Compr Psychiatry. 2013
Examination of categorical approach to symptom assessment: cross-validation of foulds' Delusions-Symptoms-States Inventory with Korean non-patient and patient groups. BMC Psychiatry. 2013
Long-term effectiveness of flexibly dosed paliperidone extended-release: comparison among patients with schizophrenia switching from risperidone and other antipsychotic agents. Curr Med Res Opin. 2013
Circadian Rhythm Characteristics in Mood Disorders: Comparison among Bipolar I Disorder, Bipolar II Disorder and Recurrent Major Depressive Disorder. Clin Psychopharmacol Neurosci. 2012
Intracerebroventricular administration of ouabain, a Na/K-ATPase inhibitor, activates mTOR signal pathways and protein translation in the rat frontal cortex. Prog Neuropsychopharmacol Biol Psychiatry. 2013
Intelligence, temperament, and personality are related to over- or under-reporting of affective symptoms by patients with euthymic mood disorder. J Affect Disord. 2013
Effectiveness of Paliperidone extended-release for patients with schizophrenia: focus on subjective improvement. Hum Psychopharmacol Clin Exp 2013
The long-term clinical benefit and effectiveness of switching to once-daily quetiapine extended release in patients with schizophrenia. Curr Med Res Opin. 2013
The prevalence of metabolic syndrome and its association with alanine aminotransferase in clozapine-treated Korean patients with schizophrenia. Int Clin Psychopharmacol. 2013
Effects of clozapine on heart rate dynamics and their relationship with therapeutic response in treatment-resistent schizophrenia. J Clin Psychopharmacol 2013
Haloperidol induces demethylation and expression of the dual specificity phosphatase 6 gene in MIA PaCa-2 human pancreatic cancer cells. Life Sci. 2012
Relationship between inflammation and metabolic syndrome following treatment with paliperidone for schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2012
Assessment of risk factors related to suicide attempts in patients with bipolar disorder. J Nerv Ment Dis. 2012
Circadian Rhythm Characteristics in Mood Disorders: Comparison among Bipolar I Disorder, Bipolar II Disorder and Recurrent Major Depressive Disorder. Clin Psychopharmacol Neurosci. 2012
The effect of clozapine on the AMPK-ACC-CPT1 pathway in the rat frontal cortex. Int J Neuropsychopharmacol. 2012
Automatic detection of seizure termination during electroconvulsive therapy using sample entropy of the electroencephalogram. Psychiatry Res. 2012
The effect of paliperidone extended release on subjective well-being and responses in patients with schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2012
Macrophage migration inhibitory factor mediates the antidepressant actions of voluntary exercise. Proc Natl Acad Sci U S A. 2012
The sustained effects of aripiprazole-augmented clozapine treatment on the psychotic symptoms and metabolic profiles of patients with refractory schizophrenia. J Clin Psychopharmacol. 2012
Childhood attention deficit hyperactivity disorder features in adult mood disorders. Compr Psychiatry. 2012
The genetic association of DUSP6 with bipolar disorder and its effect on ERK activity. Prog Neuropsychopharmacol Biol Psychiatry. 2012
Relationship between prolactin levels and subjective endocrine-related adverse effects in patients with schizophrenia receiving long-term treatment with amisulpride. Pharmacopsychiatry. 2012
Genetic association of the EGR2 gene with bipolar disorder in Korea. Exp Mol Med. 2012
The acute and long-term effectiveness of amisulpride in patients with schizophrenia: results of a 12-month open-label prospective follow-up study. Hum Psychopharmacol. 2011
Automatic detection of seizure termination during electroconvulsive therapy using sample entropy of the electroencephalogram. Psychiatry Res. 2012
The effect of cyclosporine A on the phosphorylation of the AMPK pathway in the rat hippocampus. Prog Neuropsychopharmacol Biol Psychiatry. 2011
Intracerebroventricular administration of ouabain, a Na/K-ATPase inhibitor, activates tyrosine hydroxylase through extracellular signal-regulated kinase in rat striatum. Neurochem Int. 2011
The effect of systemic injection of cyclosporin A on the phosphorylation of the PKC substrates MARCKS and GAP43 in the rat hippocampus. Neurosci Lett. 2011
The prevalence of metabolic syndrome in Korean patients with schizophrenia receiving a monotherapy with aripiprazole, olanzapine or risperidone. Prog Neuropsychopharmacol Biol Psychiatry. 2011
Impairments in executive functioning in patients with remitted and non-remitted schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2011
Association of ANK3 with bipolar disorder confirmed in East Asia. Am J Med Genet B Neuropsychiatr Genet. 2011
Imipramine activates glial cell line-derived neurotrophic factor via early growth response gene 1 in astrocytes. Prog Neuropsychopharmacol Biol Psychiatry. 2011
Repeated electroconvulsive seizure treatment in rats reduces inducibility of early growth response genes and hyperactivity in response to cocaine administration. Prog Neuropsychopharmacol Biol Psychiatry. 2011
Associations between DRDs and schizophrenia in a Korean population: multi-stage association analyses. Exp Mol Med. 2011
이외 다수
<저서>
임상진단학, 서울대학교 출판부, 1995
정신분열병, 대한신경정신의학회 역
정신분열병의 약물치료, 일조각, 1998
마음의 증상과 징후, 중앙문화사, 2000
정신의학 제 4판, 일조각, 2000
신경학 원론, 서울대학교 출판부, 2001
초발정신병, 렉스쿨, 2004
비정형 항정신병제의 임상, 서울대학교 출판부, 2004
클로자핀 임상사용의 실제, 서울대학교 출판부, 2009
리스페리돈 장기지속형 주사제 임상사용의 실제, 서울대학교 출판문화원, 2010
항정신병 약물 장기지속형 주사제 사용의 이론과 실제, 서울대학교 출판문화원, 2012
정신 증상의 역사, 중앙문화사, 2010
마음의 증상과 징후, 제 5판, 중앙문화사, 2018
전기경련치료 임상사용의 실제, 서울대학교 출판문화원
고통스러운 환청 극복하기, 이엠이즈컴퍼니, 2021
클로자핀 임상사용의 실제 3판, 서울대학교 출판부, 2024